Don’t have the person who is traveling the furthest go on first!
Schedule in time for a tech check for all speakers so you and they feel comfortable in the space and to solve any problems early.
Talks: keep people’s attention - plan breaks - but not between every talk if short! (break into morning session / lunch session / afternoon session instead)
Decide upfront if you want to factor in time for Q&A
Make it low pressure if people want to leave talks (especially if there are multiple things going on at the same time, or multiple tracks of talks)
Set up time / buffer time so that you don’t get too behind
Be strict with talk timings - don’t let people run over, give them a 5 / 2 minute warning (have a bell)
Have the running order written down online and physically in the space
Reminder slides of schedule when nothing else showing (what’s up next etc.)
If running talks, consider asking for slides in advance
Get your speakers to show up 1 hour early minimum. If possible have a private space/room for speakers where they can leave their things, and supply water, fruit, etc.
Consider recording in case people miss talks (but be aware that might change the atmosphere of a talk, and make it less personal, or the speaker may be more nervous)
Put someone who isn’t you in charge of timing for the session so it takes an immediate worry off your plate. Get them to introduce the talks and make sure things keep to schedule